Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | BCL9 | O00512 | 9/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152465 | 0.83 | BCL9 (0.51) | BCL9CTNNB1SYKFFAR4LTB4R | |
| SCHEMBL20021932 | 0.79 | GAA (0.55) | PTGDR2BCL9CTNNB1SYKALOX5AP | |
| SCHEMBL18152329 | 0.75 | BCL9 (0.79) | BCL9CTNNB1MAPTPOLB | |
| SCHEMBL18152391 | 0.75 | MGLL (0.58) | BCL9CTNNB1ALDH1A1MAPTNPC1 | |
| Trifluoroacetic Acid SCHEMBL18152377 | 0.75 | PTGDR2 (0.48) | PTGDR2BCL9CTNNB1SYKFFAR4 | |
| SCHEMBL20025817 | 0.74 | PTGDR2 (0.47) | PTGDR2BCL9CTNNB1SYKALOX5AP | |
| SCHEMBL18165099 | 0.74 | CA12 (0.45) | PTGDR2BCL9CTNNB1GRM2ALOX5AP | |
| SCHEMBL28109355 | 0.73 | ALDH1A1 (0.48) | PTGDR2ALDH1A1MAPT | |
| SCHEMBL21595671 | 0.73 | MRGPRX4 (0.48) | FFAR4ALDH1A1 | |
| SCHEMBL16741757 | 0.72 | IKBKB (0.51) | GRM2MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |