Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901201 | 0.81 | GAA (0.40) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1281660 | 0.78 | SMN1; SMN2 (0.42) | GAALMNAMAPT | |
| SCHEMBL1281568 | 0.73 | AKR1B1 (0.35) | GAAKDM4ELMNAMAPT | |
| SCHEMBL18152708 | 0.72 | RIPK1 (0.41) | — | |
| SCHEMBL1892570 | 0.70 | KDM4E (0.52) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL1918148 | 0.69 | EGLN1 (0.40) | KDM4EALDH1A1 | |
| SCHEMBL8434384 | 0.69 | KDM4E (0.40) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL7608611 | 0.68 | KDM4E (0.85) | KDM4EALDH1A1LMNAMAPTKCNJ1 | |
| SCHEMBL7608604 | 0.68 | KDM4E (0.67) | GAAKDM4EALDH1A1LMNAMAPT | |
| SCHEMBL15269858 | 0.68 | HDAC3 (0.61) | KDM4EALDH1A1LMNAMAPTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |