Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 7/20 | 0.42 |
| ▸ | CDK2 | P24941 | 7/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | BCR | P11274 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GALR2 | O43603 | 1/20 | 0.35 |
| ▸ | GALR1 | P47211 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18162602 | 0.87 | GALR2 (0.43) | CCNE1CDK2MEN1KMT2AGALR2 | |
| SCHEMBL18162581 | 0.86 | MEN1 (0.40) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL20042171 | 0.84 | BPTF (0.46) | CCNE1CDK2KMT2APIK3CACD38 | |
| Hydrochloric Acid SCHEMBL18153405 | 0.83 | BPTF (0.45) | CCNE1CDK2KMT2APIK3CACD38 | |
| SCHEMBL18162527 | 0.83 | PKM (0.50) | CCNE1CDK2ABL1BCRMEN1 | |
| SCHEMBL18153346 | 0.80 | CCNE1 (0.48) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL20042126 | 0.79 | PKM (0.51) | CCNE1CDK2MEN1KMT2AALDH1A1 | |
| SCHEMBL18153299 | 0.78 | CCNE1 (0.48) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL18162521 | 0.78 | L3MBTL1 (0.44) | CCNE1CDK2MEN1KMT2AALDH1A1 | |
| SCHEMBL18153413 | 0.77 | PKM (0.50) | CCNE1CDK2ABL1BCRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |