Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 16/20 | 0.71 |
| ▸ | BCHE | P06276 | 16/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | RGS12 | O14924 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | RAD52 | P43351 | 1/20 | 0.69 |
| ▸ | RAB9A | P51151 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128342 | 0.98 | KDM4E (0.71) | BCHEACHEKDM4EMEN1RGS12 | |
| Hydrochloric Acid SCHEMBL5144187 | 0.96 | KDM4E (0.69) | BCHEACHEKDM4EMEN1RGS12 | |
| Iodide SCHEMBL29889034 | 0.96 | KDM4E (0.74) | BCHEACHEKDM4EMEN1RGS12 | |
| Iodide SCHEMBL4618173 | 0.96 | KDM4E (0.74) | BCHEACHEKDM4EMEN1RGS12 | |
| Bromide SCHEMBL28780721 | 0.89 | KDM4E (0.81) | BCHEACHEKDM4EMEN1RGS12 | |
| SCHEMBL1017312 | 0.86 | KDM4E (0.83) | BCHEACHEKDM4EMEN1RGS12 | |
| SCHEMBL29560554 | 0.86 | KDM4E (0.83) | BCHEACHEKDM4EMEN1RGS12 | |
| Bromide SCHEMBL3360044 | 0.85 | KDM4E (0.93) | BCHEACHEKDM4EMEN1RGS12 | |
| Bromide SCHEMBL3359102 | 0.85 | KDM4E (0.93) | BCHEACHEKDM4EMEN1RGS12 | |
| Bromide SCHEMBL3359702 | 0.85 | KDM4E (0.93) | BCHEACHEKDM4EMEN1RGS12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10787745-B2 | Corrosion inhibition | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2020-09-29 | — | — | US | disclosed |
| US-20180135187-A1 | Corrosion Inhibition | SCHLUMBERGER TECHNOLOGY CORPORATION | 2018-05-17 | — | — | US | disclosed |
| US-20170335467-A1 | CORROSION INHIBITION | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2017-11-23 | — | — | US | disclosed |
| EP-3227470-A1 | CORROSION INHIBITION | Services Pétroliers Schlumberger (FR) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016167837-A1 | CORROSION INHIBITION | SCHLUMBERGER CANADA LIMITED (CA) | 2016-10-20 | — | — | WO | disclosed |
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | AUSPEX PHARMACEUTICALS, INC. | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322070-A1 | PIPERIDINE INHIBITORS OF JANUS KINASE 3 | JAK2, JAK3, PAK3 | ACHE 3892/4885BCHE 3748/4885KDM4E 568/4885 |
| US-20180135187-A1 | Corrosion Inhibition | SOD1, AOC1, NOX1 | ACHE 837/4885BCHE 3671/4885KDM4E 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.