SCHEMBL18154063

SCHEMBL18154063

c1ccc2cc(COc3ccc4ncccc4c3)ccc2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.64
ALOX5 P09917 1/20 0.58
PDE10A Q9Y233 1/20 0.54
RAB9A P51151 4/20 0.52
MRGPRX4 Q96LA9 1/20 0.49
MAOA P21397 1/20 0.48
NPC1 O15118 4/20 0.48
TEC P42680 1/20 0.48
MAPT P10636 1/20 0.48
PPARG P37231 1/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
HTT P42858 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NISCH Q9Y2I1 1/20 0.47
MET P08581 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1681256 0.88 CYP3A4 (0.73) CYP3A4ALOX5PDE10ARAB9AMAOA
SCHEMBL4035810 0.88 CYP3A4 (0.77) CYP3A4ALOX5PDE10ARAB9AMRGPRX4
SCHEMBL22315225 0.85 CYP3A4 (0.57) CYP3A4ALOX5PDE10ARAB9ANPC1
SCHEMBL13463310 0.85 CYP3A4 (0.69) CYP3A4ALOX5PDE10ARAB9AMRGPRX4
SCHEMBL12938497 0.85 ALOX5 (0.78) CYP3A4ALOX5RAB9AMRGPRX4MAOA
SCHEMBL13463408 0.84 CYP3A4 (0.58) CYP3A4ALOX5RAB9ANPC1MAPT
SCHEMBL13463295 0.84 CYP3A4 (0.58) CYP3A4ALOX5RAB9AMAOANPC1
SCHEMBL13463305 0.82 CYP3A4 (0.57) CYP3A4ALOX5RAB9AMAOAMEN1
SCHEMBL10653042 0.81 CYP3A4 (0.56) CYP3A4ALOX5PDE10ARAB9ANPC1
SCHEMBL13463304 0.81 CYP3A4 (0.56) CYP3A4MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180135187-A1 Corrosion Inhibition SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US disclosed
US-20180135187-A1 Corrosion Inhibition SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US disclosed
US-20180135187-A1 Corrosion Inhibition SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US disclosed
WO-2016167837-A1 CORROSION INHIBITION SCHLUMBERGER CANADA LIMITED (CA) 2016-10-20 WO disclosed
WO-2016167837-A1 CORROSION INHIBITION SCHLUMBERGER CANADA LIMITED (CA) 2016-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180135187-A1 Corrosion Inhibition SOD1, AOC1, NOX1 CYP3A4 1365/4885ALOX5 4173/4885PDE10A 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.