Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066558 | 0.84 | AKR1B1 (0.38) | THRBTHRAEGFRTSHRHPGD | |
| SCHEMBL18889460 | 0.77 | KMT2A (0.36) | THRBTHRAEGFRTSHRLMNA | |
| SCHEMBL17047583 | 0.69 | TSHR (0.62) | THRBTHRATSHRHPGDZDHHC20 | |
| SCHEMBL15005 | 0.69 | — | — | |
| SCHEMBL30596859 | 0.69 | FABP3 (0.43) | THRBTHRAEGFRTSHRHPGD | |
| SCHEMBL1153847 | 0.69 | FABP3 (0.43) | THRBTHRAEGFRTSHRHPGD | |
| SCHEMBL4906024 | 0.68 | LMNA (0.41) | THRBTHRAEGFRTSHRHPGD | |
| SCHEMBL15169353 | 0.68 | THRB (0.49) | THRBTSHRHPGDSMN1; SMN2LMNA | |
| Ammonia Solution, Strong SCHEMBL7047525 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3129031 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283577-A1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | Momentive Performance Materials Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168107-A1 | REACTIVE COMPOSITIONS CONTAINING MERCAPTO-FUNCTIONAL SILICON COMPOUND | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2016-10-20 | — | — | WO | disclosed |