SCHEMBL18154499

SCHEMBL18154499

Oc1ccc(Br)cc1-c1ccc(-c2cccnc2)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 8/20 0.49
CYP11B2 P19099 7/20 0.48
CYP17A1 P05093 3/20 0.46
CYP3A4 P08684 3/20 0.46
MAPT P10636 3/20 0.45
KDM4E B2RXH2 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
GLA P06280 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
IDO1 P14902 1/20 0.44
RXFP1 Q9HBX9 2/20 0.42
KMT2A Q03164 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
PRNP P04156 1/20 0.41
PPARG P37231 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NR2E3 Q9Y5X4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300994 0.81 CYP11B1 (0.59) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL21588612 0.80 CYP11B1 (0.54) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL19257504 0.80 CYP11B1 (0.54) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL13907276 0.79 CYP11B1 (0.66) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL23288097 0.76 NPC1 (0.60) CYP11B1CYP11B2CYP3A4KDM4ELMNA
SCHEMBL10016791 0.76 CYP11B1 (0.54) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL31643014 0.75 CYP11B1 (0.53) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL8173316 0.74 CYP11B1 (0.59) CYP11B1CYP11B2CYP17A1CYP3A4MAPT
SCHEMBL6222583 0.73 CYP11B1 (0.54) CYP11B1CYP11B2CYP3A4KDM4EHPGD
SCHEMBL2659900 0.73 CYP11B1 (0.54) CYP11B1CYP11B2CYP17A1CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12268086-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2025-04-01 US disclosed
CN-107531684-B Compound for organic electric element, organic electric element using same, and electronic device using same 德山新勒克斯有限公司 2020-11-24 CN disclosed
US-20180123048-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-03 US disclosed
US-20180123048-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2018-05-03 US disclosed
CN-107531684-A Organic electric element compound, organic electric element and its electronic installation using it 德山新勒克斯有限公司 2018-01-02 CN disclosed
WO-2016167491-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS 덕산네오룩스 주식회사 2016-10-20 WO disclosed
WO-2016167491-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC APPARATUS 덕산네오룩스 주식회사 2016-10-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12268086-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof PIEZO1, OCIAD1, LEF1 CYP11B1 962/4885CYP11B2 1193/4885CYP17A1 761/4885
US-20180123048-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF PIEZO1, OCIAD1, LEF1 CYP11B1 962/4885CYP11B2 1193/4885CYP17A1 761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.