Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423665 | 1.00 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDLCKHSD17B10 | |
| SCHEMBL17403186 | 0.80 | KDM4E (0.76) | ALDH1A1KDM4EHPGDLCKHSD17B10 | |
| SCHEMBL18154594 | 0.80 | MAOB (0.70) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL6592913 | 0.78 | MAOB (0.71) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL4209634 | 0.77 | KDM4E (0.76) | ALDH1A1KDM4EHPGDLCKHSD17B10 | |
| SCHEMBL15702989 | 0.77 | MAOB (0.58) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL15963945 | 0.77 | KDM4E (0.69) | ALDH1A1KDM4EHPGDLCKHSD17B10 | |
| SCHEMBL4206653 | 0.76 | MAOB (0.68) | MAOAMAOB | |
| SCHEMBL15963909 | 0.76 | KDM4E (0.56) | ALDH1A1KDM4EHPGDLCKHSD17B10 | |
| SCHEMBL28026514 | 0.75 | MAOB (0.70) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283461-B1 | NOVEL COUMARIN DERIVATIVE FOR DETECTION OF CYSTEINE AND PROCESS FOR THE SYNTHESIS THEREOF | COUNCIL SCIENT IND RES (IN) | 2022-03-30 | — | — | EP | disclosed |
| US-10030002-B2 | Coumarin derivative for detection of cysteine and process for the synthesis thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-07-24 | — | — | US | disclosed |
| US-20180093963-A1 | NOVEL COUMARIN DERIVATIVE FOR DETECTION OF CYSTEINE AND PROCESS FOR THE SYNTHESIS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-04-05 | — | — | US | disclosed |
| EP-3283461-A1 | NOVEL COUMARIN DERIVATIVE FOR DETECTION OF CYSTEINE AND PROCESS FOR THE SYNTHESIS THEREOF | Council of Scientific and Industrial Research (IN) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016166773-A1 | NOVEL COUMARIN DERIVATIVE FOR DETECTION OF CYSTEINE AND PROCESS FOR THE SYNTHESIS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180093963-A1 | NOVEL COUMARIN DERIVATIVE FOR DETECTION OF CYSTEINE AND PROCESS FOR THE SYNTHESIS THEREOF | ALDH7A1, LANCL1, CPB1 | ALDH1A1 244/4885KDM4E 3253/4885HPGD 1166/4885 |
| US-10030002-B2 | Coumarin derivative for detection of cysteine and process for the synthesis thereof | ALDH7A1, LANCL1, CPA1 | ALDH1A1 162/4885KDM4E 3333/4885HPGD 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.