Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 12/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704549 | 0.96 | — | — | |
| Ethylene Glycol SCHEMBL672311 | 0.89 | THRB (0.36) | THRBTHRACYP1A2ALDH1A1PKM | |
| SCHEMBL5532392 | 0.88 | THRB (0.37) | THRBTHRAFFAR3HDAC3HDAC1 | |
| SCHEMBL30190455 | 0.87 | THRB (0.36) | THRBTHRAFFAR3HDAC3HDAC1 | |
| SCHEMBL181262 | 0.87 | THRB (0.36) | THRBTHRAFFAR3HDAC3HDAC1 | |
| SCHEMBL20590547 | 0.86 | THRB (0.35) | THRBTHRACYP1A2ALDH1A1PKM | |
| SCHEMBL18154865 | 0.86 | THRB (0.35) | THRBTHRACYP1A2ALDH1A1PKM | |
| SCHEMBL1535860 | 0.86 | THRB (0.35) | THRBTHRACYP1A2ALDH1A1PKM | |
| SCHEMBL673452 | 0.83 | THRB (0.33) | THRBTHRACYP1A2ALDH1A1PKM | |
| SCHEMBL19085520 | 0.83 | CYP1A2 (0.45) | CYP1A2ALDH1A1HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5401505-A | Microcapsules from polyfunctional aziridines | MINNESOTA MINING AND MANUFACTURING (US) | 1995-03-28 | — | — | US | claimed |
| US-5169632-A | MICROCAPSULES FROM POLYFUNCTIONAL AZIRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-12-08 | — | — | US | claimed |
| US-8309657-B2 | Rubber composition | BRIDGESTONE CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20110196086-A1 | RUBBER COMPOSITION | BRIDGESTONE CORPORATION (JP) | 2011-08-11 | — | — | US | disclosed |
| EP-2336233-A1 | RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2011-06-22 | — | — | EP | disclosed |
| EP-0508576-B1 | Microcapsules from polyfunctional aziridines | MINNESOTA MINING & MFG (US) | 1995-07-19 | — | — | EP | disclosed |
| US-5401505-A | Microcapsules from polyfunctional aziridines | MINNESOTA MINING AND MANUFACTURING (US) | 1995-03-28 | — | — | US | disclosed |
| US-5169632-A | MICROCAPSULES FROM POLYFUNCTIONAL AZIRIDINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-12-08 | — | — | US | disclosed |