Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7801882 | 0.89 | NOTUM (0.51) | MBTD1L3MBTL3L3MBTL1CHRM4MMP3 | |
| SCHEMBL987932 | 0.85 | MBTD1 (0.52) | MBTD1L3MBTL3L3MBTL1HRH3NOTUM | |
| SCHEMBL2448590 | 0.82 | MAPT (0.47) | L3MBTL3L3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL14924425 | 0.82 | GPR119 (0.47) | MAPTALDH1A1DRD2DRD3 | |
| SCHEMBL7334686 | 0.82 | MAPT (0.54) | HRH3MAPTDRD2DRD3 | |
| SCHEMBL24319216 | 0.82 | SLC6A2 (0.47) | L3MBTL3L3MBTL1MAPTSLC6A2SLC6A4 | |
| SCHEMBL8133600 | 0.82 | HRH3 (0.50) | CHRM4HRH3MAPTNOTUMKDM4E | |
| SCHEMBL1663774 | 0.82 | USP2 (0.62) | MBTD1L3MBTL3L3MBTL1MMP3MMP8 | |
| SCHEMBL2448833 | 0.82 | ADRA2C (0.50) | HRH3MAPTCHRM2KDM4EALDH1A1 | |
| SCHEMBL4703341 | 0.81 | CYP2D6 (0.50) | MBTD1L3MBTL3L3MBTL1CHRM4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174263-B | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-118598798-A | Preparation method for directly synthesizing arylamine compound based on aromatic hydrocarbon and fatty amine | 沈阳药科大学 | 2024-09-06 | — | — | CN | disclosed |
| CN-114174263-A | Non-lysosomal glucosylceramidase inhibitors and uses thereof | 阿勒克图治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| EP-3283488-A1 | HETEROCYCLES USEFUL AS IDO AND TDO INHIBITORS | Hangzhou Innogate Pharma Co., Ltd. (CN) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016165613-A1 | HETEROCYCLES USEFUL AS IDO AND TDO INHIBITORS | HANGZHOU INNOGATE PHARMA CO., LTD. (CN) | 2016-10-20 | — | — | WO | disclosed |