Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18155314 | 0.90 | ALDH1A1 (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18155309 | 0.90 | ALDH1A1 (0.41) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18155301 | 0.87 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18155310 | 0.85 | ALDH1A1 (0.38) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL16433512 | 0.84 | CHRM2 (0.42) | ALDH1A1LMNA | |
| SCHEMBL16433514 | 0.84 | CHRM2 (0.42) | ALDH1A1LMNA | |
| SCHEMBL18155305 | 0.83 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18155304 | 0.83 | MMP1 (0.37) | MMP1MMP2MMP3MMP9MMP13 | |
| SCHEMBL18155292 | 0.83 | KCNH2 (0.41) | LMNAKCNH2FOLH1 | |
| SCHEMBL16433515 | 0.78 | MMP1 (0.35) | MMP1MMP2MMP3MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114014-A1 | B-LACTAM COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-27 | — | — | US | disclosed |
| US-9469610-B2 | β-lactam compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114014-A1 | B-LACTAM COMPOUNDS | COASY, BBOX1, GNE | AGTR2 3847/4885MMP1 3261/4885MMP2 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.