Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3146589 | 0.86 | PHLPP2 (0.44) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL6882694 | 0.85 | ALDH1A1 (0.50) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL11490011 | 0.84 | CYP3A4 (0.44) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL3943609 | 0.83 | PHLPP2 (0.42) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL5624307 | 0.82 | TP53 (0.41) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL2069920 | 0.81 | TP53 (0.68) | TP53CYP3A4ALDH1A1TSHROPRM1 | |
| SCHEMBL5624837 | 0.81 | MTNR1A (0.45) | TP53CYP3A4ALDH1A1MAPK1TSHR | |
| SCHEMBL18455023 | 0.81 | EGFR (0.46) | CYP3A4ALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL10893728 | 0.79 | TRPM8 (0.55) | TP53ALDH1A1TSHRLMNAOPRM1 | |
| SCHEMBL16125596 | 0.78 | TP53 (0.54) | TP53ALDH1A1TSHRTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895176-B1 | RIVAROXABAN INTERMEDIATE AND PREPARATION THEREOF | WANBURY LTD (IN) | 2016-10-19 | — | — | EP | disclosed |