Penicillamine

Penicillamine

SCHEMBL1815588

CC(C)(S)[C@@H](N)C(=O)O.CC(C)(S)[C@@H](N)C(=O)O.CC(C)(S)[C@@H](N)C(=O)O.CC(C)(S)[C@@H](N)C(=O)O.S.S

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.95
PTGS1 P23219 2/20 0.95
MAPT P10636 2/20 0.95
SLC7A5 Q01650 2/20 0.36
SLC7A11 Q9UPY5 1/20 0.35
GRIK1 P39086 1/20 0.32
ENPEP Q07075 3/20 0.32
SLC1A3 P43003 1/20 0.31
SLC1A2 P43004 1/20 0.31
SLC1A1 P43005 1/20 0.31
HPGD P15428 2/20 0.30
HSD17B10 Q99714 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
ABCB11 O95342 1/20 0.30
F2 P00734 1/20 0.30
TP53 P04637 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Penicillamine SCHEMBL9195712 1.00 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL28222280 1.00 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL8509793 1.00 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL4911772 1.00 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL4343 0.97
Dl-Penicillamine SCHEMBL57527 0.97
Dl-Penicillamine SCHEMBL4344 0.97
Dl-Penicillamine SCHEMBL22322162 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL129296 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL159653 0.97 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12098391-B2 Generation of hepatocytes from pluripotent stem cells ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2024-09-24 US claimed
CN-109072438-B Methods of depositing a metal or metal alloy onto a substrate surface and including substrate surface activation 德国艾托特克公司 2021-08-13 CN claimed
US-10287552-B2 Generation of hepatocytes from pluripotent stem cells ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2019-05-14 US claimed
WO-2014004784-A1 GENERATION OF HEPATOCYTES FROM PLURIPOTENT STEM CELLS ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2014-01-03 WO claimed
EP-0397437-A1 Method of treating human eyes and a composition thereof PILKINGTON VISIONCARE HOLDINGS, INC. (US) 1990-11-14 EP claimed
JP-3027314-A None JP disclosed
CN-118851961-B Process method for synthesizing D-penicillamine 中科全同(大连)医药科技有限公司 2025-01-24 CN disclosed
CN-118851961-A Process method for synthesizing D-penicillamine 中科全同(大连)医药科技有限公司 2024-10-29 CN disclosed
US-12098391-B2 Generation of hepatocytes from pluripotent stem cells ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2024-09-24 US disclosed
US-20220304923-A1 USE OF ORAL CHEW FOR MODULATING ORAL MICROBIOTA AND IMPROVING ORAL HEALTH MARS, INCORPORATED (US) 2022-09-29 US disclosed
US-20220304335-A1 MODULATION OF ORAL MICROBIOTA MARS, INCORPORATED (US) 2022-09-29 US disclosed
EP-3979813-A1 MODULATION OF ORAL MICROBIOTA Mars Incorporated (US) 2022-04-13 EP disclosed
WO-1998006435-A2 COMPOSITIONS OF ANTICHLAMYDIAL AGENTS FOR THE DIAGNOSIS AND MANAGEMENT OF INFECTION CAUSED BY $i(CHLAMYDIA) VANDERBILT UNIVERSITY (US) 1998-02-19 WO disclosed
EP-0675712-A4 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS. HANDELMAN JOSEPH H (US) 1996-11-06 EP disclosed
EP-0675712-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, Joseph H. (US) 1995-10-11 EP disclosed
US-5411991-A Applying to human skin, beards, reaction with cysteine GILLETTE COMPANY, THE, A DELAWARE CORPORATION 1995-05-02 US disclosed
WO-1994014428-A1 REDUCTION OF HAIR GROWTH EMPLOYING SULFHYDRYL REACTIVE COMPOUNDS HANDELMAN, JOSEPH, H. (US) 1994-07-07 WO disclosed
JP-H0327314-A COMPOSITION FOR TREATING HUMAN EYE PILKINGTON VISIONCARE INC 1991-02-05 JP disclosed
EP-0397437-A1 Method of treating human eyes and a composition thereof PILKINGTON VISIONCARE HOLDINGS, INC. (US) 1990-11-14 EP disclosed
EP-0397437-A1 Method of treating human eyes and a composition thereof PILKINGTON VISIONCARE HOLDINGS, INC. (US) 1990-11-14 EP disclosed