Dl-Penicillamine

Dl-Penicillamine

SCHEMBL22322162

CC(C)(S)C(N)C(=O)O.CC(C)(S)C(N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
PTGS1 P23219 2/20 1.00
MAPT P10636 2/20 1.00
SLC7A5 Q01650 2/20 0.38
SLC7A11 Q9UPY5 1/20 0.36
ENPEP Q07075 3/20 0.33
GRIK1 P39086 1/20 0.33
SLC1A3 P43003 1/20 0.32
SLC1A2 P43004 1/20 0.32
SLC1A1 P43005 1/20 0.32
HPGD P15428 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
ABCB11 O95342 1/20 0.32
F2 P00734 1/20 0.32
TP53 P04637 1/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Penicillamine SCHEMBL4344 1.00
Penicillamine SCHEMBL4343 1.00
Dl-Penicillamine SCHEMBL159653 1.00 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Dl-Penicillamine SCHEMBL57527 1.00
Penicillamine SCHEMBL129296 1.00 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL603349 1.00 ALDH1A1 (1.00) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL10789333 0.97 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL3138111 0.97 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11
Penicillamine SCHEMBL6654084 0.97
Penicillamine SCHEMBL7932147 0.97 ALDH1A1 (0.95) ALDH1A1PTGS1MAPTSLC7A5SLC7A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN SOCPRA SCIENCES SANTÉ ET HUMAINES S.E.C. (CA) 2022-06-02 US disclosed
EP-3921331-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN Socpra Sciences Santé Et Humaines S.E.C. (CA) 2021-12-15 EP disclosed
WO-2020160685-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN SOCPRA Sciences Sante et Humaines S.E.C. (CA) 2020-08-13 WO disclosed
CN-101360487-A Pharmaceutical formulation for sulfur-containing drugs in liquid dosage forms CHILDRENS MEDICAL CT (US) 2009-02-04 CN disclosed
CN-101291683-A Methods and compositions for treating disease NEOPRO LABS LLC (US) 2008-10-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220168383-A1 NEUROTENSINERGIC AGONISTS AND METHODS OF USING SAME PREVENTING OR TREATING PAIN VIP, NTSR2, VIPR2 ALDH1A1 1872/4885PTGS1 105/4885MAPT 1971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.