Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 3/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dl-Penicillamine SCHEMBL4344 | 1.00 | — | — | |
| Penicillamine SCHEMBL4343 | 1.00 | — | — | |
| Dl-Penicillamine SCHEMBL159653 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 | |
| Dl-Penicillamine SCHEMBL57527 | 1.00 | — | — | |
| Penicillamine SCHEMBL603349 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 | |
| Dl-Penicillamine SCHEMBL22322162 | 1.00 | ALDH1A1 (1.00) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 | |
| Penicillamine SCHEMBL10789333 | 0.97 | ALDH1A1 (0.95) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 | |
| Penicillamine SCHEMBL3138111 | 0.97 | ALDH1A1 (0.95) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 | |
| Penicillamine SCHEMBL6654084 | 0.97 | — | — | |
| Penicillamine SCHEMBL7932147 | 0.97 | ALDH1A1 (0.95) | ALDH1A1PTGS1MAPTSLC7A5SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110927135-B | Method for rapidly and visually distinguishing different chiral penicillamine and racemic penicillamine in sample | 无锡市疾病预防控制中心 | 2023-12-29 | — | — | CN | claimed |
| CN-110927135-A | Method for rapidly and visually distinguishing different chiral penicillamine and racemic penicillamine in sample | 无锡市疾病预防控制中心 | 2020-03-27 | — | — | CN | claimed |
| CN-110927135-B | Method for rapidly and visually distinguishing different chiral penicillamine and racemic penicillamine in sample | 无锡市疾病预防控制中心 | 2023-12-29 | — | — | CN | disclosed |
| CN-110927135-A | Method for rapidly and visually distinguishing different chiral penicillamine and racemic penicillamine in sample | 无锡市疾病预防控制中心 | 2020-03-27 | — | — | CN | disclosed |
| US-20120101098-A1 | 3,28-DISUBSTITUTED BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-04-26 | — | — | US | disclosed |
| EP-1868613-B1 | POLYMORPHS OF 3-O-(3',3'-DIMETHYLSUCCINYL) BETULINIC ACID DI-N-METHYL-D-GLUCAMINE | MYREXIS INC (US) | 2012-03-07 | — | — | EP | disclosed |
| US-20110152229-A1 | BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | DUKE UNIVERSITY | 2011-06-23 | — | — | US | disclosed |
| US-20110045501-A1 | ST2-BASED DENGUE FEVER DIAGNOSTIC | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-02-24 | — | — | US | disclosed |
| US-20080200550-A1 | Inhibition of Hiv-1 Replication by Disruption of the Processing of the Viral Capsid-Spacer Peptide 1 Protein | V.I. TECHNOLOGIES, INC. (US) | 2008-08-21 | — | — | US | disclosed |
| US-20040097555-A1 | Concomitant drugs | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152229-A1 | BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | BET1, PGGT1B, RABGGTB | ALDH1A1 3610/4885PTGS1 841/4885MAPT 708/4885 |
| US-20040097555-A1 | Concomitant drugs | TNF, CHUK, CNKSR1 | ALDH1A1 3292/4885PTGS1 78/4885MAPT 2113/4885 |
| US-20120101098-A1 | 3,28-DISUBSTITUTED BETULINIC ACID DERIVATIVES AS ANTI-HIV AGENTS | BET1, CD4, PGGT1B | ALDH1A1 2309/4885PTGS1 807/4885MAPT 1605/4885 |
| US-20080200550-A1 | Inhibition of Hiv-1 Replication by Disruption of the Processing of the Viral Capsid-Spacer Peptide 1 Protein | SP1, CPSF1, SUB1 | ALDH1A1 3292/4885PTGS1 2149/4885MAPT 3223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.