Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.53 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.46 |
| ▸ | PADI4 | Q9UM07 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20223300 | 0.97 | CYP11B1 (0.58) | CYP11B1CYP11B2PLK4MEN1KMT2A | |
| SCHEMBL20225455 | 0.95 | CYP11B1 (0.51) | CYP11B1CYP11B2PLK4MEN1KMT2A | |
| SCHEMBL18157753 | 0.85 | PADI4 (0.43) | MEN1KMT2ARAB9ANPC1ALK | |
| SCHEMBL18157762 | 0.84 | ALK (0.50) | CYP11B1CYP11B2PLK4MEN1KMT2A | |
| SCHEMBL18160331 | 0.83 | MAPT (0.47) | PLK4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18157755 | 0.82 | NPC1 (0.50) | PLK4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL28555372 | 0.82 | NPC1 (0.50) | PLK4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18157765 | 0.77 | ALK (0.50) | PLK4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18157747 | 0.77 | ALK (0.50) | PLK4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL18160335 | 0.76 | KDM4E (0.43) | CYP11B1CYP11B2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834514-B2 | Antibiotic sensitivity-restoring and photosensitive agents | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2016172193-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH RESEARCH FOUNDATION (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155286-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | CYP11B1 4651/4885CYP11B2 4652/4885PLK4 1462/4885 |
| US-20160304453-A1 | ANTIBIOTIC SENSITIVITY-RESTORING AND PHOTOSENSITIVE AGENTS | XPA, PPOX, ALAD | CYP11B1 4651/4885CYP11B2 4652/4885PLK4 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.