Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 9/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.50 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18157755 | 1.00 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18157762 | 0.91 | ALK (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18160186 | 0.91 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18157739 | 0.91 | MAPT (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18160289 | 0.91 | NFE2L2 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18157733 | 0.91 | NFE2L2 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18157735 | 0.91 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL18180644 | 0.91 | MAPT (0.49) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL5636833 | 0.88 | MEN1 (0.46) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL5636837 | 0.88 | MEN1 (0.46) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109678862-B | Preparation method of polysubstituted distyryl indole derivative | 青岛科技大学 | 2021-04-27 | — | — | CN | claimed |
| CN-109678862-B | Preparation method of polysubstituted distyryl indole derivative | 青岛科技大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-109678862-B | Preparation method of polysubstituted distyryl indole derivative | 青岛科技大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-109678862-B | Preparation method of polysubstituted distyryl indole derivative | 青岛科技大学 | 2021-04-27 | — | — | CN | disclosed |