SCHEMBL18157920

SCHEMBL18157920

CN(c1ccccc1O)c1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.49
ALDH1A1 P00352 6/20 0.47
MAPT P10636 4/20 0.47
SMN1; SMN2 Q16637 4/20 0.47
CA2 P00918 4/20 0.47
NPC1 O15118 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
ALOX15 P16050 3/20 0.47
LMNA P02545 3/20 0.47
EGFR P00533 2/20 0.47
FYN P06241 2/20 0.47
MMP9 P14780 2/20 0.47
HPGD P15428 2/20 0.47
RECQL P46063 2/20 0.47
HSD17B10 Q99714 2/20 0.47
RAB9A P51151 2/20 0.47
KDM4E B2RXH2 2/20 0.47
CA4 P22748 2/20 0.47
CA12 O43570 1/20 0.47
GMNN O75496 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6874443 0.89 TRPA1 (0.43) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL6877796 0.85 CXCR2 (0.47) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
Bromide SCHEMBL10436173 0.84 CXCR2 (0.46) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL134637 0.83 EP300 (0.52) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL31276399 0.83 EP300 (0.52) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL27502134 0.82 TAAR1 (0.42) CXCR2CA2CA12HIF1ATSHR
Hydrochloric Acid SCHEMBL28984485 0.81 EP300 (0.56) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL27682040 0.81 ALDH1A1 (0.45) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL6878929 0.80 ALDH1A1 (0.43) CXCR2ALDH1A1MAPTSMN1; SMN2CA2
SCHEMBL20310421 0.79 ALDH1A1 (0.43) CXCR2ALDH1A1MAPTSMN1; SMN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20180094086-A1 NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER FUJIFILM CORPORATION (JP) 2018-04-05 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 CXCR2 3008/4885ALDH1A1 2313/4885MAPT 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.