SCHEMBL18157974

SCHEMBL18157974

O=C(O)CNC(Cc1cccc(O)n1)c1cccc(O)n1

nearest known ligand 0.33

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MME P08473 4/20 0.32
ALDH1A1 P00352 2/20 0.32
ACE P12821 2/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
ECE1 P42892 1/20 0.32
BLM P54132 1/20 0.32
NPEPPS P55786 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
FTO Q9C0B1 3/20 0.30
EGLN1 Q9GZT9 2/20 0.30
KDM5B Q9UGL1 1/20 0.30
KDM2A Q9Y2K7 1/20 0.30
BBOX1 O75936 1/20 0.30
EGLN2 Q96KS0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18158012 0.83 CPB2 (0.43) MAPT
SCHEMBL18158008 0.83 KMT2A (0.40) MEN1KMT2A
SCHEMBL18157986 0.79 PTGER2 (0.38)
SCHEMBL18157995 0.76 ADORA1 (0.37)
SCHEMBL20682492 0.75 TAS1R3 (0.36) NPSR1
SCHEMBL7570942 0.74 CTSA (0.36) NPSR1
SCHEMBL18157982 0.74 PTPRA (0.51) ALDH1A1HPGDMEN1MAPTKMT2A
SCHEMBL18157998 0.70 EGLN1 (0.39) ALDH1A1FTOEGLN1
SCHEMBL18160693 0.70 NPSR1 (0.44) NPSR1FTOEGLN1KDM5BKDM2A
SCHEMBL7561352 0.70 KDM4E (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE FUJIFILM CORPORATION (JP) 2017-08-10 US disclosed
US-20160304730-A1 NEAR INFRARED RADIATION-ABSORBING COMPOSITION, NEAR INFRARED RADIATION CUT-OFF FILTER AND PRODUCTION METHOD THEREFOR, AND CAMERA MODULE AND PRODUCTION METHOD THEREFOR FUJIFILM CORPORATION (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170227690-A1 NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE C9, SET, CRY1 MME 2217/4885ALDH1A1 2313/4885ACE 3028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.