Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.45 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18158947 | 0.87 | MEN1 (0.54) | MEN1KMT2AALDH1A1HPGDLMNA | |
| SCHEMBL18158949 | 0.87 | MEN1 (0.54) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15227011 | 0.82 | MEN1 (0.63) | MEN1KMT2AALDH1A1CYP2C9GSTP1 | |
| SCHEMBL15227594 | 0.82 | SMN1; SMN2 (0.66) | MEN1KMT2AALDH1A1GSTP1GSTM2 | |
| SCHEMBL15227162 | 0.82 | MEN1 (0.63) | MEN1KMT2AALDH1A1GSTP1GSTM2 | |
| SCHEMBL21081382 | 0.81 | MEN1 (0.47) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL1817217 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1CYP2C9CYP1A2 | |
| SCHEMBL21046089 | 0.77 | MEN1 (0.76) | MEN1KMT2AALDH1A1CYP2C9GSTP1 | |
| SCHEMBL29859154 | 0.76 | TSHR (0.47) | ALDH1A1APEX1CASP6LMNASMN1; SMN2 | |
| SCHEMBL18397215 | 0.76 | TSHR (0.47) | ALDH1A1APEX1CASP6LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304459-A1 | NOVEL COMPOUND, PRODUCTION METHOD THEREFOR, AND APPLICATION THEREFOR | VIP, MRPL21, THEM6 | MEN1 514/4885KMT2A 4096/4885ALDH1A1 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.