Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816404 | 0.87 | L3MBTL1 (0.61) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1819203 | 0.81 | MEN1 (0.57) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1819572 | 0.81 | ALDH1A1 (0.54) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1817759 | 0.81 | KMT2A (0.53) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1818273 | 0.80 | MEN1 (0.52) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1818910 | 0.78 | MEN1 (0.68) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1819620 | 0.78 | MAPT (0.51) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18158937 | 0.78 | MEN1 (0.60) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1818074 | 0.78 | MEN1 (0.50) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1816569 | 0.78 | MEN1 (0.50) | ALDH1A1CYP2C9MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2011060199-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | ALDH1A1 4190/4885CYP2C9 3001/4885MEN1 818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.