Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23242772 | 0.94 | ESR1 (0.44) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL1817923 | 0.92 | ESR1 (0.45) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL2455000 | 0.92 | ESR1 (0.47) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL28606956 | 0.92 | ESR1 (0.50) | ESR1ESR2ALDH1A1HSD17B1HSD17B2 | |
| SCHEMBL2859818 | 0.92 | ALDH1A1 (0.50) | ESR1ESR2ALDH1A1HIF1ACYP1B1 | |
| SCHEMBL2991961 | 0.90 | SOS1 (0.48) | ESR1ESR2ALDH1A1SOS1HSD17B1 | |
| SCHEMBL27610205 | 0.90 | ESR1 (0.51) | ESR1ESR2ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL2995209 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HIF1ACYP1B1HSD17B10HSD17B1 | |
| SCHEMBL31290733 | 0.90 | ALDH1A1 (0.52) | ALDH1A1HIF1ACYP1B1HSD17B10SOS1 | |
| SCHEMBL23242753 | 0.90 | GPR84 (0.42) | ESR1ESR2ALDH1A1HIF1ACYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2012-08-30 | — | — | US | disclosed |
| WO-2011054442-A2 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120217449-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, DDT, ERCC1 | ESR1 45/4885ESR2 135/4885ALDH1A1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.