Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALPL | P05186 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817376 | 0.86 | RAB9A (0.53) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL1806737 | 0.75 | GAA (0.39) | RAB9AMAPTKDM4EALDH1A1LMNA | |
| SCHEMBL1430763 | 0.74 | ALPL (0.55) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL16763424 | 0.74 | ALPL (0.55) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL1456739 | 0.72 | ALPL (0.54) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL23500795 | 0.71 | ALPL (0.56) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL1359 | 0.71 | ALPL (0.52) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL9900502 | 0.69 | HPGDS (0.58) | RAB9AMAPTNPC1L3MBTL1ALPL | |
| SCHEMBL1815529 | 0.69 | HCAR2 (0.53) | ALPLTP53MAPK1 | |
| SCHEMBL7008825 | 0.69 | ALPL (0.50) | RAB9AMAPTNPC1L3MBTL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493858-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | Orion Corporation (FI) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051540-A9 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011051540-A1 | ANDROGEN RECEPTOR MODULATING COMPOUNDS | ORION CORPORATION (FI) | 2011-05-05 | — | — | WO | disclosed |