Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713112 | 0.81 | RARB (0.41) | — | |
| SCHEMBL8499337 | 0.78 | CTNNB1 (0.39) | GRM4SMN1; SMN2 | |
| SCHEMBL7709229 | 0.76 | RARB (0.41) | — | |
| SCHEMBL7713267 | 0.75 | ACACB (0.33) | KDM4C | |
| SCHEMBL4373679 | 0.74 | APP (0.30) | — | |
| SCHEMBL7715091 | 0.74 | RARB (0.42) | MAPK1SMN1; SMN2 | |
| SCHEMBL7714840 | 0.73 | CA12 (0.35) | SMN1; SMN2 | |
| SCHEMBL8681448 | 0.73 | NPC1 (0.39) | PTGER4 | |
| SCHEMBL20636862 | 0.70 | BACE1 (0.36) | — | |
| SCHEMBL8197285 | 0.70 | AKR1B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2400951-A1 | TOPICAL FOAM COMPOSITION | Stiefel Research Australia Pty Ltd (AU) | 2012-01-04 | — | — | EP | disclosed |
| WO-2010096868-A1 | TOPICAL FOAM COMPOSITION | STIEFEL RESEARCH AUSTRALIA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |