Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4372497 | 0.85 | AKR1B1 (0.31) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL4373679 | 0.82 | APP (0.30) | — | |
| SCHEMBL8671663 | 0.80 | RARA (0.45) | AKR1B1AKR1B10MAPTAKR1A1 | |
| SCHEMBL4373634 | 0.77 | LMNA (0.42) | MAPT | |
| SCHEMBL9054289 | 0.77 | MAPT (0.41) | AKR1B1MAPT | |
| SCHEMBL9817651 | 0.77 | RARB (0.53) | — | |
| SCHEMBL7566669 | 0.76 | RARA (0.35) | AKR1B1MAPT | |
| Hydrochloric Acid SCHEMBL21750681 | 0.76 | MAPT (0.44) | AKR1B1MAPT | |
| SCHEMBL20636862 | 0.75 | BACE1 (0.36) | — | |
| SCHEMBL20636854 | 0.74 | RARA (0.37) | AKR1B1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003569-A2 | STERILE BIOERODIBLE IMPLANT DEVICE WITH IMPROVED BIOCOMPATABILITY AND METHOD | Allergan Sales, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007418-A2 | STERILE BIOERODIBLE IMPLANT DEVICE WITH IMPROVED BIOCOMPATABILITY AND METHOD | ALLERGAN SALES, INC. (US) | 1999-02-18 | — | — | WO | disclosed |