Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 7/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 7/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166460 | 0.91 | AKR1C3 (0.38) | MAP3K5P2RX3P2RX2 | |
| SCHEMBL18166342 | 0.89 | P2RX3 (0.41) | MAP3K5P2RX3P2RX2 | |
| SCHEMBL18166394 | 0.88 | ROCK1 (0.38) | MAP3K5P2RX3P2RX2 | |
| SCHEMBL10244559 | 0.87 | P2RX3 (0.45) | MAP3K5P2RX3P2RX2 | |
| SCHEMBL18166349 | 0.85 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166380 | 0.85 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166269 | 0.84 | P2RX3 (0.38) | MAP3K5P2RX3P2RX2PTGS2 | |
| SCHEMBL18166366 | 0.84 | P2RX3 (0.36) | P2RX3P2RX2PTGS2 | |
| SCHEMBL18036393 | 0.84 | P2RX3 (0.43) | MAP3K5P2RX3P2RX2 | |
| SCHEMBL18036367 | 0.82 | P2RX3 (0.35) | MAP3K5P2RX3P2RX2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |