Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.52 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166424 | 0.90 | P2RX3 (0.54) | P2RX3P2RX2TRPV1ACACBACACA | |
| SCHEMBL18166465 | 0.89 | P2RX3 (0.52) | P2RX3P2RX2TRPV1ACACBGPR139 | |
| SCHEMBL18166436 | 0.88 | P2RX3 (0.53) | P2RX3P2RX2TRPV1ACACBACACA | |
| SCHEMBL10243721 | 0.87 | P2RX3 (0.68) | P2RX3P2RX2 | |
| SCHEMBL18166335 | 0.85 | P2RX3 (0.59) | P2RX3P2RX2MAPTLMNA | |
| SCHEMBL18166427 | 0.85 | P2RX3 (0.55) | P2RX3P2RX2TRPV1ACACBACACA | |
| SCHEMBL18166293 | 0.84 | P2RX3 (0.57) | P2RX3P2RX2TRPV1ACACBGPR139 | |
| SCHEMBL18166399 | 0.84 | P2RX3 (0.46) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18166361 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2TRPV1ACACBGPR139 | |
| SCHEMBL18166319 | 0.82 | P2RX3 (0.53) | P2RX3P2RX2TRPV1ACACBGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |