Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166398 | 0.89 | P2RX3 (0.57) | P2RX3P2RX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18166444 | 0.86 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL10244645 | 0.86 | P2RX3 (0.60) | P2RX3P2RX2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL18166437 | 0.85 | P2RX3 (0.45) | P2RX3P2RX2SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL18166392 | 0.85 | P2RX3 (0.50) | P2RX3P2RX2SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL18166311 | 0.85 | P2RX3 (0.49) | P2RX3P2RX2MAPTTP53LMNA | |
| SCHEMBL18166433 | 0.84 | P2RX3 (0.49) | P2RX3P2RX2MAPTL3MBTL1ADORA2A | |
| SCHEMBL18166332 | 0.84 | EPHX1 (0.52) | P2RX3P2RX2RAB9ANPC1MAPT | |
| SCHEMBL18166272 | 0.83 | P2RX3 (0.47) | P2RX3P2RX2SMN1; SMN2MAPTKDM4E | |
| SCHEMBL18166400 | 0.83 | P2RX3 (0.61) | P2RX3P2RX2MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |