Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.57 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166444 | 0.89 | P2RX3 (0.48) | P2RX3P2RX2 | |
| SCHEMBL18166378 | 0.89 | P2RX3 (0.48) | P2RX3P2RX2MAPTSMN1; SMN2LMNA | |
| SCHEMBL18166368 | 0.87 | P2RX3 (0.47) | P2RX3P2RX2EPHX1HPGDSMEN1 | |
| SCHEMBL18166311 | 0.87 | P2RX3 (0.49) | P2RX3P2RX2MAPTLMNA | |
| SCHEMBL18166332 | 0.86 | EPHX1 (0.52) | P2RX3P2RX2MAPTEPHX1LMNA | |
| SCHEMBL10244399 | 0.86 | P2RX3 (0.71) | P2RX3P2RX2MAPTSMN1; SMN2LMNA | |
| SCHEMBL18166392 | 0.86 | P2RX3 (0.50) | P2RX3P2RX2MAPTEPHX1SMN1; SMN2 | |
| SCHEMBL18166414 | 0.85 | P2RX3 (0.48) | P2RX3P2RX2MAPTSMN1; SMN2LMNA | |
| SCHEMBL18166433 | 0.85 | P2RX3 (0.49) | P2RX3P2RX2MAPTLMNA | |
| SCHEMBL18166437 | 0.84 | P2RX3 (0.45) | P2RX3P2RX2MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |