Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.51 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10243939 | 0.86 | P2RX3 (0.67) | P2RX3P2RX2 | |
| SCHEMBL18166285 | 0.86 | P2RX3 (0.50) | P2RX3P2RX2TRPV1LMNAMAPT | |
| SCHEMBL18166293 | 0.84 | P2RX3 (0.57) | P2RX3P2RX2TRPV1LMNAALDH1A1 | |
| SCHEMBL18036400 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2TRPV1LMNAMAPT | |
| SCHEMBL18036457 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2TRPV1LMNAMAPT | |
| SCHEMBL18166427 | 0.83 | P2RX3 (0.55) | P2RX3P2RX2TRPV1LMNAMAPT | |
| SCHEMBL18166335 | 0.83 | P2RX3 (0.59) | P2RX3P2RX2LMNAMAPTALDH1A1 | |
| SCHEMBL18166291 | 0.83 | P2RX3 (0.44) | P2RX3P2RX2LMNAMAPTALDH1A1 | |
| SCHEMBL18166409 | 0.83 | P2RX3 (0.54) | P2RX3P2RX2TRPV1LMNAMAPT | |
| SCHEMBL18166344 | 0.83 | P2RX3 (0.50) | P2RX3P2RX2TRPV1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |