Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18166318 | 0.85 | P2RX3 (0.50) | P2RX3P2RX2HCRTR1HCRTR2TRPV1 | |
| SCHEMBL18166285 | 0.85 | P2RX3 (0.50) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18166372 | 0.84 | P2RX3 (0.53) | P2RX3P2RX2PHGDHTRPV1MAPT | |
| SCHEMBL18166293 | 0.83 | P2RX3 (0.57) | P2RX3P2RX2TRPV1LMNAALDH1A1 | |
| SCHEMBL18036359 | 0.83 | P2RX3 (0.52) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18036400 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18036457 | 0.83 | P2RX3 (0.53) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18166382 | 0.83 | P2RX3 (0.51) | P2RX3P2RX2TRPV1MAPTLMNA | |
| SCHEMBL18166409 | 0.82 | P2RX3 (0.54) | P2RX3P2RX2NPC1RAB9ATRPV1 | |
| SCHEMBL18166361 | 0.81 | P2RX3 (0.53) | P2RX3P2RX2TRPV1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-B1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | HOFFMANN LA ROCHE (CH) | 2016-10-26 | — | — | EP | claimed |