Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 4/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1818074 | 0.79 | MEN1 (0.50) | SMN1; SMN2POLBALDH1A1HTTCDC7 | |
| SCHEMBL1818167 | 0.78 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL1816057 | 0.78 | SMN1; SMN2 (0.45) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL1819037 | 0.78 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL1816092 | 0.75 | PTPN11 (0.44) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL6195410 | 0.75 | POLB (0.50) | NPC1RAB9ASMN1; SMN2POLBPKM | |
| SCHEMBL27002710 | 0.74 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL1819828 | 0.74 | ALDH1A1 (0.51) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1817318 | 0.74 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2POLBPIN1 | |
| SCHEMBL7901310 | 0.74 | KMT2A (0.60) | ALDH1A1HTTNPSR1PKMGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | US | disclosed |
| WO-2011060199-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212918-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, BTD | NPC1 1272/4885RAB9A 628/4885SMN1; SMN2 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.