Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789957 | 0.81 | KDM4E (0.53) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL7671680 | 0.78 | KMT2A (0.51) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL1818167 | 0.78 | SMN1; SMN2 (0.45) | KMT2AALDH1A1HPGDPKMLMNA | |
| SCHEMBL8788592 | 0.77 | KMT2A (0.55) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL8412537 | 0.76 | KMT2A (0.53) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL22809569 | 0.76 | PKM (0.52) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL7821174 | 0.75 | PKM (0.65) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL6394768 | 0.75 | HSD17B10 (0.59) | KDM4EALDH1A1HPGDNPSR1GAA | |
| SCHEMBL7676239 | 0.75 | NPSR1 (0.56) | KMT2AKDM4EALDH1A1HPGDNPSR1 | |
| SCHEMBL1816752 | 0.74 | NPC1 (0.42) | ALDH1A1NPSR1GAAPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6191280-B1 | REACTING SUBSTITUTED 2-HALOPYRIDINE DERIVATIVE WITH A THIO COMPOUND IN PRESENCE OF COPPER CATALYST TO GIVE A PYRIDINE THIOETHER, AND THEN OXIDIZING THE THIOETHER INTERMEDIATE TO FORM SULFOXIDE OR SULFONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | disclosed |
| EP-0984935-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054139-A1 | METHOD FOR PRODUCING SUBSTITUTED THIOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-03 | — | — | WO | disclosed |