Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.51 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.51 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | KDM6B | O15054 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18167999 | 0.90 | KDM4E (0.55) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL19347397 | 0.86 | KDM4E (0.67) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2639071 | 0.85 | KDM4E (0.56) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638289 | 0.83 | KDM4E (0.54) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638608 | 0.83 | KDM4E (0.62) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2639455 | 0.83 | KDM4E (0.54) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638590 | 0.82 | KDM4E (0.53) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638902 | 0.81 | KDM4E (0.51) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638388 | 0.80 | KDM4E (0.51) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL2638073 | 0.80 | KDM4E (0.51) | KDM4ELMNAALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951086-B2 | Indazolecarboxamides, processes for their preparation, pharmaceutical preparations comprising them and their use for producing medicaments | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-04-24 | — | — | US | disclosed |
| US-20160311833-A1 | NOVEL INDAZOLECARBOXAMIDES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS COMPRISING THEM AND THEIR USE FOR PRODUCING MEDICAMENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160311833-A1 | NOVEL INDAZOLECARBOXAMIDES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS COMPRISING THEM AND THEIR USE FOR PRODUCING MEDICAMENTS | MALT1, APC, UACA | KDM4E 1366/4885LMNA 390/4885ALOX15 1777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.