SCHEMBL1817115

SCHEMBL1817115

Fc1c(F)c(-c2ccc(Br)s2)c2nsnc2c1-c1ccc(Br)s1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.36
HSD17B10 Q99714 2/20 0.36
ALOX12 P18054 2/20 0.36
MEN1 O00255 1/20 0.36
ALOX15 P16050 1/20 0.36
KMT2A Q03164 1/20 0.36
RAB9A P51151 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NPC1 O15118 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
TP53 P04637 1/20 0.34
HPGD P15428 1/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
NCOA1 Q15788 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16541851 0.91 MEN1 (0.31) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL16185944 0.88 DHODH (0.34) MAPTHSD17B10ALOX12MEN1KMT2A
SCHEMBL28399995 0.82 MAPT (0.32) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL18665537 0.82 KDM4E (0.32) MAPTMEN1KMT2AKDM4EPPARG
SCHEMBL20163207 0.81 MAPT (0.36) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL19942280 0.81 MAPT (0.38) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL14052845 0.81 MAPT (0.43) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL16361670 0.81 SNCA (0.41) MAPTHSD17B10ALOX12MEN1ALOX15
SCHEMBL22479100 0.81 NPC1 (0.32) MAPTHSD17B10ALOX12MEN1KMT2A
SCHEMBL21772851 0.80 RXFP1 (0.40) MAPTHSD17B10ALOX12MEN1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
EP-2897183-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2020-04-29 EP disclosed
EP-2897183-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2020-04-29 EP disclosed
US-10428085-B2 Asymmetric benzotrichalcogenophene compound and polymer NATIONAL CHIAO TUNG UNIVERSITY (TW) 2019-10-01 US disclosed
EP-2828904-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2019-06-12 EP disclosed
EP-2828904-B1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES RAYNERGY TEK INC (TW) 2019-06-12 EP disclosed
US-20180370986-A1 ASYMMETRIC BENZOTRICHALCOGENOPHENE COMPOUND AND POLYMER NATIONAL CHIAO TUNG UNIVERSITY (TW) 2018-12-27 US disclosed
US-10093680-B2 Asymmetric benzotrichalcogenophene compound, synthesis method thereof and polymer NATIONAL CHIAO TUNG UNIVERSITY (TW) 2018-10-09 US disclosed
US-20180237452-A1 ASYMMETRIC BENZOTRICHALCOGENOPHENE COMPOUND, SYNTHESIS METHOD THEREOF AND POLYMER NATIONAL CHIAO TUNG UNIVERSITY (TW) 2018-08-23 US disclosed
US-20130200354-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
US-20130200355-A1 Conjugated Polymers and Their Use in Optoelectronic Devices POLYERA CORPORATION (US) 2013-08-08 US disclosed
EP-2501698-A1 FLUORINATED MONOMERS, OLIGOMERS AND POLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES National Research Council of Canada (CA) 2012-09-26 EP disclosed
US-20120232237-A1 Fluorinated Monomers, Oligomers and Polymers for Use in Organic Electronic Devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-09-13 US disclosed
US-20120232237-A1 Fluorinated Monomers, Oligomers and Polymers for Use in Organic Electronic Devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-09-13 US disclosed
US-20120232237-A1 Fluorinated Monomers, Oligomers and Polymers for Use in Organic Electronic Devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-09-13 US disclosed
WO-2012054910-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES POLYERA CORPORTION (US) 2012-04-26 WO disclosed
WO-2012054910-A1 CONJUGATED POLYMERS AND THEIR USE IN OPTOELECTRONIC DEVICES POLYERA CORPORTION (US) 2012-04-26 WO disclosed
WO-2011060526-A1 FLUORINATED MONOMERS, OLIGOMERS AND POLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-05-26 WO disclosed
WO-2011060526-A1 FLUORINATED MONOMERS, OLIGOMERS AND POLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180237452-A1 ASYMMETRIC BENZOTRICHALCOGENOPHENE COMPOUND, SYNTHESIS METHOD THEREOF AND POLYMER TST, BTF3, TPR MAPT 638/4885HSD17B10 1858/4885ALOX12 3452/4885
US-10428085-B2 Asymmetric benzotrichalcogenophene compound and polymer TST, TPR, TEC MAPT 264/4885HSD17B10 1500/4885ALOX12 1704/4885
US-10093680-B2 Asymmetric benzotrichalcogenophene compound, synthesis method thereof and polymer TST, BTF3, BRI3BP MAPT 595/4885HSD17B10 2095/4885ALOX12 3370/4885
US-20120232237-A1 Fluorinated Monomers, Oligomers and Polymers for Use in Organic Electronic Devices NR1I2, NR1I3, NR2C2 MAPT 2770/4885HSD17B10 3236/4885ALOX12 1352/4885
US-20180370986-A1 ASYMMETRIC BENZOTRICHALCOGENOPHENE COMPOUND AND POLYMER TST, TPR, TEC MAPT 264/4885HSD17B10 1500/4885ALOX12 1704/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.