SCHEMBL1817138

SCHEMBL1817138

COC(=O)Cc1cc([N+](=O)[O-])ccc1Br

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
ALDH1A1 P00352 4/20 0.46
PDGFRB P09619 1/20 0.46
FGFR1 P11362 1/20 0.46
PDGFRA P16234 1/20 0.46
FLT1 P17948 1/20 0.46
FGFR3 P22607 1/20 0.46
KDR P35968 1/20 0.46
GLA P06280 1/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 3/20 0.45
MAPT P10636 3/20 0.43
GAA P10253 1/20 0.43
CYP1A2 P05177 1/20 0.43
PTGS2 P35354 1/20 0.43
PKM P14618 1/20 0.43
HTT P42858 1/20 0.43
LMNA P02545 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16619742 0.88 CYP1A2 (0.47) POLBALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL17630097 0.86 MAPT (0.49) ALDH1A1KMT2AMEN1MAPTGAA
SCHEMBL502591 0.84 PDGFRB (0.53) POLBALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL30664602 0.82 LMNA (0.48) POLBALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL2556486 0.82 LMNA (0.48) POLBALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL9156278 0.82 ALDH1A1 (0.58) ALDH1A1KMT2AMEN1MAPTGAA
SCHEMBL14439930 0.82 POLB (0.50) POLBALDH1A1PDGFRBFGFR1PDGFRA
SCHEMBL3737258 0.81 CYP1A2 (0.64) POLBALDH1A1KMT2AMEN1MAPT
SCHEMBL3737256 0.81 CYP1A2 (0.64) POLBALDH1A1KMT2AMEN1MAPT
SCHEMBL4098621 0.81 PDGFRB (0.58) POLBALDH1A1PDGFRBFGFR1PDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
US-8461134-B2 Boron-containing small molecules ANACOR PHARMACEUTICALS, INC. (US) 2013-06-11 US disclosed
US-20110172187-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-07-14 US disclosed
WO-2011060196-A1 BORON-CONTAINING SMALL MOLECULES ANACOR PHARMACEUTICALS, INC. (US) 2011-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172187-A1 BORON-CONTAINING SMALL MOLECULES BCL6B, BCL6, BTD POLB 721/4885ALDH1A1 4190/4885PDGFRB 922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.