Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817138 | 0.88 | POLB (0.47) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL28676925 | 0.86 | MAPT (0.49) | CYP1A2ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18982074 | 0.86 | MEN1 (0.49) | CYP1A2ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1626207 | 0.84 | PDGFRB (0.53) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL31001012 | 0.84 | PDGFRB (0.53) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL29777188 | 0.84 | CYP1A2 (0.68) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL2133926 | 0.84 | CYP1A2 (0.68) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL6597479 | 0.82 | CYP1A2 (0.47) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 | |
| SCHEMBL1626187 | 0.82 | GAA (0.58) | CYP1A2ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1625685 | 0.82 | MAPT (0.49) | CYP1A2PDGFRBFGFR1PDGFRAFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2026-01-22 | — | — | US | disclosed |
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | NEXYS THERAPEUTICS, INC. (US) | 2024-12-17 | — | — | US | disclosed |
| EP-4472953-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | Nexys Therapeutics, Inc. (US) | 2024-12-11 | — | — | EP | disclosed |
| US-20240383893-A1 | Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof | HAIHE BIOPHARMA CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | US | disclosed |
| EP-4400493-A1 | HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF | Haihe Biopharma Co., Ltd. (CN) | 2024-07-17 | — | — | EP | disclosed |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | disclosed |
| CN-117980293-A | Hydroxamic acid compound with ENPP1 inhibitory activity and application thereof | 上海海和药物研究开发股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| WO-2023036289-A1 | HYDROXAMIC ACID COMPOUND HAVING ENPP1 INHIBITORY ACTIVITY AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2023-03-16 | — | — | WO | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156181-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2015049629-A1 | IMIDAZOQUINOLINE COMPOUNDS AS BROMODOMAIN INHIBITORS | Piramal Enterprises Limited (IN) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383893-A1 | Hydroxamic Acid Compound Having ENPP1 Inhibitory Activity and Use Thereof | ENPP1, ENPP2, ENPP3 | CYP1A2 4427/4885PDGFRB 2367/4885FGFR1 1221/4885 |
| US-12371408-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | CYP1A2 86/4885PDGFRB 567/4885FGFR1 301/4885 |
| US-20260022099-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, NR1H4, CNR1 | CYP1A2 249/4885PDGFRB 768/4885FGFR1 544/4885 |
| US-20240279185-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | CYP1A2 86/4885PDGFRB 567/4885FGFR1 301/4885 |
| US-12168646-B2 | Aryl hydrocarbon receptor agonists and uses thereof | AHR, ARNT, NR1H2 | CYP1A2 86/4885PDGFRB 567/4885FGFR1 301/4885 |
| US-20240208913-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | AHR, ARNT, NR1H2 | CYP1A2 86/4885PDGFRB 567/4885FGFR1 301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.