Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20293061 | 0.80 | MET (0.44) | CCNT1CDK9KCNH3RIPK2CYP1A2 | |
| SCHEMBL3869962 | 0.75 | KCNH2 (0.42) | CHEK1CCNT1CDK9KCNH3RIPK2 | |
| SCHEMBL4316875 | 0.75 | PTGER4 (0.40) | CHEK1CCNT1CDK9KCNH3RIPK2 | |
| SCHEMBL1192778 | 0.74 | CCNT1 (0.47) | CHEK1CCNT1CDK9PIM1PIM2 | |
| SCHEMBL29911325 | 0.73 | USP30 (0.43) | CYP1A2CYP2C19PIM1 | |
| SCHEMBL18571792 | 0.73 | USP30 (0.43) | CYP1A2CYP2C19PIM1 | |
| SCHEMBL16040798 | 0.72 | CCNT1 (0.49) | CHEK1CCNT1CDK9KCNH3PIM1 | |
| SCHEMBL2113586 | 0.71 | PTGES (0.41) | KCNH2ATMATR | |
| SCHEMBL780200 | 0.70 | PABPC1 (0.42) | CYP1A2CYP2C19 | |
| SCHEMBL20374462 | 0.70 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |