Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.42 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171928 | 0.96 | LIPE (0.44) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL15430194 | 0.83 | MEN1 (0.49) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL18171926 | 0.82 | LIPE (0.63) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL15430193 | 0.81 | LMNA (0.51) | LMNAALDH1A1MEN1NR1I2CHRM2 | |
| SCHEMBL3789201 | 0.81 | CYP1A2 (0.52) | LMNAHTR1BMEN1NR1I2CHRM2 | |
| SCHEMBL3785252 | 0.78 | MCHR1 (0.44) | LIPENPC1POLBLMNAHTR1B | |
| SCHEMBL18171929 | 0.78 | LIPE (0.63) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL15430195 | 0.77 | KDR (0.40) | LIPEENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL29953651 | 0.76 | LIPE (0.56) | LIPEENPP2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL7632353 | 0.74 | LIPG (0.56) | LIPEENPP2L3MBTL1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3285923-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | Univation Technologies, LLC (US) | 2018-02-28 | — | — | EP | disclosed |
| WO-2016172097-A1 | BRIDGED BI-AROMATIC LIGANDS AND OLEFIN POLYMERIZATION CATALYSTS PREPARED THEREFROM | UNIVATION TECHNOLOGIES, LLC (US) | 2016-10-27 | — | — | WO | disclosed |