SCHEMBL18172301

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4528209	0.89	MEN1 (0.40)	PIM1HSD17B10MEN1KMT2AACHE
	SCHEMBL20061673	0.82	IRAK1 (0.42)	CYP1A2CYP2C19MEN1KMT2ACNR1
	SCHEMBL14905758	0.82	LMNA (0.46)	PIM1LMNAMEN1KMT2AEGFR
	SCHEMBL1256953	0.81	ACHE (0.56)	CYP3A4CYP1A2CYP2D6LMNACYP2C19
	SCHEMBL11235791	0.79	CYP3A4 (0.48)	CYP3A4CYP1A2CYP2D6LMNAHIF1A
	SCHEMBL18172287	0.79	MAPT (0.47)	CYP1A2CYP2D6LMNACYP2C19MEN1
	SCHEMBL1257037	0.77	KMT2A (0.51)	PIM1CYP3A4CYP2D6LMNAMEN1
	SCHEMBL3344759	0.77	RXFP1 (0.52)	CYP3A4CYP1A2CYP2D6LMNAHIF1A
	SCHEMBL3951404	0.77	TOP2A (0.45)	PIM1CYP3A4CYP1A2CYP2D6LMNA
	SCHEMBL1251922	0.77	L3MBTL1 (0.46)	CYP3A4CYP2D6LMNACYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.