Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14417894 | 0.92 | FFAR1 (0.54) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL13997198 | 0.89 | PYCR1 (0.47) | PYCR1FFAR1FFAR4APPHTR2A | |
| SCHEMBL3397750 | 0.84 | CYP1A2 (0.58) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL27563099 | 0.79 | FFAR1 (0.54) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8910688 | 0.79 | POLB (0.58) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL28772070 | 0.79 | FFAR1 (0.50) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL651586 | 0.77 | APP (0.67) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL5401236 | 0.77 | APP (0.67) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL28266545 | 0.76 | PYCR1 (0.49) | PYCR1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL21244052 | 0.75 | LTA4H (0.55) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2494408-A1 | PHOTOCHROMIC MATERIALS | Transitions Optical, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011053615-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2011-05-05 | — | — | WO | disclosed |