Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | VCP | P55072 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28772074 | 0.92 | MEN1 (0.58) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL3397750 | 0.84 | CYP1A2 (0.58) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27563099 | 0.79 | FFAR1 (0.54) | FFAR1FFAR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28772070 | 0.79 | FFAR1 (0.50) | MEN1ALDH1A1MAPTKMT2AFFAR1 | |
| SCHEMBL1817267 | 0.79 | PYCR1 (0.60) | ALDH1A1FFAR1FFAR4CYP1A2CYP3A4 | |
| SCHEMBL28772071 | 0.79 | PTGES (0.46) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL21244052 | 0.79 | LTA4H (0.55) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL7503092 | 0.78 | FFAR1 (0.57) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2831992 | 0.77 | APP (0.67) | POLBMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15014207 | 0.77 | APP (0.67) | POLBMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656314-B | Preparation method of internal alkyne compound | 许昌学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-114656314-A | Preparation method of internal alkyne compound | 许昌学院 | 2022-06-24 | — | — | CN | disclosed |
| US-5703378-A | Materials for the scavanging of hydrogen at high temperatures | SANDIA CORPORATION (US) | 1997-12-30 | — | — | US | disclosed |