Butylamine

Butylamine

SCHEMBL18173554

CCCCN.CCOC(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
ALOX15 P16050 1/20 0.42
CPB2 Q96IY4 1/20 0.42
DNM1 Q05193 8/20 0.40
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TSHR P16473 1/20 0.40
EPHX1 P07099 1/20 0.40
GABBR2 O75899 1/20 0.39
GABRR1 P24046 1/20 0.39
GABBR1 Q9UBS5 1/20 0.39
LMNA P02545 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetradecylamine SCHEMBL16774862 0.91 DNM1 (0.54) CYP1A2CPB2DNM1ALDH1A1MEN1
Propylamine SCHEMBL18173555 0.88 CYP1A2 (0.48) CYP1A2ALOX15CPB2ALDH1A1LMNA
Hexane SCHEMBL8017946 0.85 AKR1B1 (0.48) ALOX15ALDH1A1MEN1KMT2ATSHR
Butylamine SCHEMBL910037 0.84 ALDH1A1 (0.52) CYP1A2DNM1ALDH1A1TSHREPHX1
SCHEMBL28558128 0.83 GPR84 (0.50) ALOX15ALDH1A1MEN1KMT2ATSHR
Ethylamine SCHEMBL910370 0.83
Butylamine SCHEMBL18173909 0.81 DNM1 (0.43) CYP1A2ALOX15DNM1ALDH1A1MEN1
Hydrazine SCHEMBL27272031 0.80
Butylamine SCHEMBL2547783 0.80
Butylamine SCHEMBL3530621 0.80 DNM1 (0.53) CYP1A2ALOX15DNM1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3286266-A1 IMPROVED COATING SYSTEMS, USE THEREOF FOR COATING COMPONENTS AND COMPONENTS COATED THEREWITH FOR RAIL VEHICLES AND AIRCRAFTS Mankiewicz Gebr. & Co. GmbH & Co. KG (DE) 2018-02-28 EP disclosed
WO-2016169543-A1 IMPROVED COATING SYSTEMS, USE THEREOF FOR COATING COMPONENTS AND COMPONENTS COATED THEREWITH FOR RAIL VEHICLES AND AIRCRAFTS MANKIEWICZ GEBR. & CO. GMBH & CO. KG (DE) 2016-10-27 WO disclosed