Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | LPL | P06858 | 9/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1814466 | 0.94 | ALDH1A1 (0.44) | ALDH1A1EGFRLPLLIPGSNCA | |
| SCHEMBL21176048 | 0.82 | LPL (0.39) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL18171891 | 0.81 | EGFR (0.40) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL20622695 | 0.80 | LPL (0.45) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL7603285 | 0.80 | LPL (0.47) | ALDH1A1LPLLIPGSNCA | |
| SCHEMBL24145964 | 0.79 | EGFR (0.46) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL14721612 | 0.79 | EGFR (0.43) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL18614454 | 0.79 | LPL (0.37) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL933108 | 0.79 | LPL (0.44) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL31503579 | 0.78 | TLR9 (0.52) | ALDH1A1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321296-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | Bayer Schering Pharma Aktiengesellschaft (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010020363-A1 | SUBSTITUTED 5-AMINOPYRAZOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-02-25 | — | — | WO | disclosed |