Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | LPL | P06858 | 9/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30472985 | 0.94 | EGFR (0.40) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL23247903 | 0.83 | ALPL (0.40) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL18171886 | 0.81 | PDGFRB (0.54) | EGFRLPLLIPGDGAT1PDGFRB | |
| SCHEMBL21176048 | 0.81 | LPL (0.39) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL1817443 | 0.81 | ALDH1A1 (0.44) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL30379252 | 0.81 | LPL (0.44) | EGFRLPLLIPGSNCAIRAK4 | |
| SCHEMBL18171882 | 0.81 | NUDT1 (0.40) | LPLLIPG | |
| SCHEMBL7603285 | 0.79 | LPL (0.47) | LPLLIPGSNCADGAT1PDGFRB | |
| SCHEMBL1530858 | 0.78 | PDGFRB (0.47) | SNCAPDGFRBPDGFRA | |
| SCHEMBL18614454 | 0.78 | LPL (0.37) | EGFRLPLLIPGSNCAIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016170163-A1 | SUBSTITUTED QUINOXALINES AND BENZOTRIAZINE P70S6 KINASE INHIBITORS | SENTINEL ONCOLOGY LIMITED (GB) | 2016-10-27 | — | — | WO | disclosed |