Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 3/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 3/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24461841 | 1.00 | ALB (0.49) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL24239462 | 0.92 | ALB (0.44) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL21305215 | 0.92 | ALB (0.44) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL12227120 | 0.91 | NOD1 (0.44) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL14902998 | 0.88 | CASP2 (0.51) | ALBSIRT5TLR2NOD1EPHX2 | |
| SCHEMBL10027319 | 0.87 | MEN1 (0.52) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL10130532 | 0.85 | SIRT5 (0.60) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL10033607 | 0.85 | ALB (0.45) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL14902999 | 0.84 | GLP1R (0.46) | ALBSIRT5TLR2NOD1ROCK2 | |
| SCHEMBL878812 | 0.82 | SIRT5 (0.44) | ALBSIRT5TLR2NOD1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9475839-B2 | Peptide-based inhibitor of interleukin-10 or interferon-gamma signaling | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-10-25 | — | — | US | disclosed |