SCHEMBL18174632

SCHEMBL18174632

Cc1ccnc(-c2ccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5C)cc4)c4ccccc34)cc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.50
GRM4 Q14833 1/20 0.41
CCR1 P32246 1/20 0.40
CCR5 P51681 1/20 0.40
CCR8 P51685 1/20 0.40
DHODH Q02127 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
RECQL P46063 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
TGFBR1 P36897 1/20 0.37
HAVCR2 Q8TDQ0 1/20 0.35
PIK3CA P42336 2/20 0.35
CYP19A1 P11511 1/20 0.35
CYP17A1 P05093 3/20 0.35
CYP1A2 P05177 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174732 0.93 CYP2A6 (0.49) CYP2A6GRM4CCR1CCR5CCR8
SCHEMBL18174683 0.90 CYP2A6 (0.50) CYP2A6CCR1CCR5CCR8DHODH
SCHEMBL18174564 0.85 GRM4 (0.49) GRM4DHODHHAVCR2CYP19A1CYP17A1
SCHEMBL18174555 0.85 CCR1 (0.55) CYP2A6CCR1CCR5CCR8KDM4E
SCHEMBL18174684 0.83 CYP3A4 (0.49) CYP2A6GRM4CCR1CCR5CCR8
SCHEMBL18174727 0.83 CYP2A6 (0.49) CYP2A6CCR1CCR5CCR8DHODH
SCHEMBL15161039 0.81 GRM4 (0.46) GRM4DHODHPIK3CACYP19A1CYP17A1
SCHEMBL18174647 0.81 DYRK1A (0.44) GRM4PIK3CACYP17A1CYP1A2IRAK4
SCHEMBL18174729 0.80 CYP2A6 (0.42) CYP2A6GRM4DHODHTGFBR1CYP19A1
SCHEMBL18174663 0.80 GRM4 (0.37) CYP2A6GRM4DHODHKDM4ETGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed