SCHEMBL18174732

SCHEMBL18174732

Cc1ccnc(-c2cccc(-c3c4ccccc4c(-c4ccc(-c5ccncc5C)cc4)c4ccccc34)c2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.49
GRM4 Q14833 1/20 0.38
TGFBR1 P36897 1/20 0.38
CYP17A1 P05093 3/20 0.37
CCR1 P32246 1/20 0.36
CCR5 P51681 1/20 0.36
CCR8 P51685 1/20 0.36
BRD4 O60885 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CYP1A2 P05177 2/20 0.36
CNR1 P21554 1/20 0.35
ELANE P08246 1/20 0.35
PIK3CA P42336 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174632 0.93 CYP2A6 (0.50) CYP2A6GRM4TGFBR1CYP17A1CCR1
SCHEMBL18174727 0.91 CYP2A6 (0.49) CYP2A6TGFBR1CYP17A1CCR1CCR5
SCHEMBL18174729 0.88 CYP2A6 (0.42) CYP2A6GRM4TGFBR1CYP17A1BRD4
SCHEMBL18174750 0.86 GRM4 (0.43) GRM4CYP17A1BRD4CYP1A2CYP19A1
SCHEMBL18174752 0.86 CYP3A4 (0.47) CYP2A6GRM4CYP17A1CCR1CCR5
SCHEMBL15161088 0.84 CYP2A6 (0.63) CYP2A6CCR1CCR5CCR8KDM4E
SCHEMBL18174577 0.83 CYP2A6 (0.54) CYP2A6TGFBR1CCR1CCR5CCR8
SCHEMBL18174717 0.83 PIK3CA (0.41) GRM4CYP17A1CYP1A2PIK3CACYP19A1
SCHEMBL18174683 0.83 CYP2A6 (0.50) CYP2A6CYP17A1CCR1CCR5CCR8
SCHEMBL18174753 0.83 PIK3CA (0.45) GRM4CYP17A1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed