SCHEMBL18174637

SCHEMBL18174637

Cc1ccc2c(-c3ccc(-c4cccnc4)cc3C)c3ccccc3c(-c3ccc(-c4cccnc4)cc3C)c2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 1/20 0.47
MAPT P10636 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CYP17A1 P05093 2/20 0.46
MAP2K4 P45985 1/20 0.46
MKNK1 Q9BUB5 1/20 0.45
MKNK2 Q9HBH9 1/20 0.45
CYP11B1 P15538 3/20 0.43
CYP11B2 P19099 2/20 0.43
CYP19A1 P11511 1/20 0.43
CHEK1 O14757 2/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174556 0.92 SLC2A1 (0.54) SLC2A1NPC1RAB9ATP53MAPT
SCHEMBL18174573 0.91 SLC2A1 (0.49) SLC2A1CYP17A1MKNK1MKNK2CYP11B1
SCHEMBL18174609 0.88 SLC2A1 (0.47) SLC2A1CYP17A1MKNK1MKNK2CYP11B1
SCHEMBL18174617 0.88 SLC2A1 (0.47) SLC2A1CYP17A1MKNK1MKNK2CYP11B1
SCHEMBL18174593 0.86 CYP11B2 (0.61) SLC2A1NPC1RAB9ACYP17A1MKNK1
SCHEMBL10030073 0.85 MAP2K4 (0.51) NPC1RAB9ATP53SMN1; SMN2CYP17A1
SCHEMBL18174707 0.84 SLC2A1 (0.46) SLC2A1NPC1RAB9ATP53MAPT
SCHEMBL10300950 0.83 MAP2K4 (0.50) NPC1RAB9AMAPTSMN1; SMN2CYP17A1
SCHEMBL10030066 0.83 MAP2K4 (0.50) NPC1RAB9ATP53SMN1; SMN2CYP17A1
SCHEMBL18174679 0.82 SLC2A1 (0.46) SLC2A1CYP17A1MKNK1MKNK2CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed