SCHEMBL18174593

SCHEMBL18174593

Cc1cc(-c2cccnc2)ccc1-c1c2ccccc2c(-c2ccc(-c3cccnc3)cc2C)c2cc(-c3ccc4ccccc4c3)ccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 11/20 0.61
CYP11B1 P15538 11/20 0.61
CYP19A1 P11511 7/20 0.61
CYP17A1 P05093 4/20 0.61
SLC2A1 P11166 1/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
TLR9 Q9NR96 1/20 0.42
TLR8 Q9NR97 1/20 0.42
TLR7 Q9NYK1 1/20 0.42
MKNK1 Q9BUB5 1/20 0.42
MKNK2 Q9HBH9 1/20 0.42
CHEK1 O14757 1/20 0.42
AURKA O14965 1/20 0.42
DAPK3 O43293 1/20 0.42
JAK2 O60674 1/20 0.42
PRKD3 O94806 1/20 0.42
MAP4K4 O95819 1/20 0.42
PAK4 O96013 1/20 0.42
ABL1 P00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174601 0.92 CYP11B1 (0.56) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL10032212 0.91 CYP11B2 (0.58) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174573 0.90 SLC2A1 (0.49) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174556 0.88 SLC2A1 (0.54) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174609 0.88 SLC2A1 (0.47) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174617 0.88 SLC2A1 (0.47) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174637 0.86 SLC2A1 (0.48) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1
SCHEMBL18174596 0.86 MAPK9 (0.43) CYP11B2CYP11B1CYP19A1CYP17A1CHEK1
SCHEMBL10300977 0.86 CYP11B2 (0.73) CYP11B2CYP11B1CYP19A1CYP17A1NPC1
SCHEMBL10032223 0.85 CYP11B2 (0.51) CYP11B2CYP11B1CYP19A1CYP17A1SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed